Abstract
Summary
An analysis of the phosphoryl-ated intermediates of the liver and brain of hypophysectomized rats with and without ACTH was made. The decreased ability of hypophysectomized rats to synthesize glycogen from glucose was restored to normal by ACTH. Phosphoprotein phosphorus levels also returned to normal with ACTH. The anaerobic glycolysis of the brain of hypophysectomized rats was reduced 20% below that of normal rats but this was restored to normal by the administration of ACTH.
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