Abstract
Summary
Comparison of the average weight gains made by young, growing rats (offspring of B12-depleted animals) on diets of varying fat and carbohydrate content, with and without B12, shows that subcutaneous administration of B12 produces increased weight gains in both sexes on all four of the rations studied. It appears that when the calories are derived primarily from carbohydrate the vitamin exerts a greater effect on weight gain in young, growing, female rats than in their littermate males. The weight stimulating effect of B12 is more marked in females on high carbohydrate diets than in littermate sisters on diets of like protein content but with the calories provided by fat or a mixture of fat and carbohydrate
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