Abstract
Summary and conclusions
1. One hundred and sixty-three male Swiss mice weighing between 17 and 20 g were implanted sub-cutaneously with fragments of sarcoma 37 and then injected subcutaneously or intravenously beginning on the day of implantation or 7 days thereafter with hyaluronidase, heat inactivated hyaluronidase, or physiological salt solution.
2. The results on the effect of hyaluronidase administered subcutaneously or intravenously were somewhat variable, from which it is concluded that there was no effect on the growth or invasibility of implanted sarcoma 37. Neither was there metastasis to distant organs.
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