Abstract
Summary
1. The mean blood and packed cell volumes of 22 adult male rats, as measured by transfused tagged cells, was found to be 4.95 and 2.32 ml per 100 g of body weight respectively.
2. The mean blood and packed cell volumes of six of the 22 rats, assayed by the hemoglobin extraction method, were found to be 4.92 and 2.32 ml per 100 g of body weight.
3. The efficiency of perfusion for the total rat was 95%. This corresponds to a possible error in blood volume, introduced by removal of tagged transfused cells from the recipients circulation, no greater than 5%.
4. Comparison of the blood volume of various tissues taken from maximally bled rats with the blood volumes of similar tissues taken from perfused rats indicates that perfusion is least effective for spleen and most effective for kidney and brain.
The authors wish to thank B. Baldwin, J. Gordon, and M. Kern for technical assistance.
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