Abstract
Summary
The electrophoretic distribution of the serum proteins of 20 patients with disseminated lupus erythematosus showed a lowered albumin content with a considerable increase in the α2- as well as γ-globulin concentration. The sera of 5 patients were studied before therapy with cortisone and adrenocorticotropin (ACTH). After a clinical remission had been produced by these agents, it was found that the albumin and γ-globulin components progressed towards normal levels whereas the α2-globulin fraction remained unchanged.
Thanks are due to Dr. George Baehr and the members of the First Medical Service for their cooperation throughout this study. The technical help of Sheldon S. Gilbert and Harold Corey is acknowledged with appreciation.
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