Abstract
Summary
1. Radioactive estrone sulfate shows no definite localization in any of the target organs following intravenous or subcutaneous injection into mature female rats in spite of marked estrogenic response. 2. Estrone sulfate is rapidly hydrolyzed in the body. 3. Estrone sulfate is excreted not only by way of the urinary tract but considerable amounts find their way into feces.
We wish to thank Dr. Edward C. Reifenstein, Jr., and Ayerst, McKenna and Harrison for the labeled and non-labeled estrone sulfate which they generously supplied.
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