Abstract
Summary
A relatively stable emulsion of α-tocopherylhydroquinone in propylene glycol and water can be formed. Best results were obtained when propylene glycol solutions containing 100 mg/cc of the hydroquinone were used and the concentration of propylene glycol in the emulsion was 10%. Such emulsions contained 90% of the added hydroquinone and were relatively stable. The emulsion was useful for intravenous administration in rabbits and produced no significant local reaction in the blood vessels. The emulsion has not been administered parenterally in patients; its injection by the intravenous route in man must await further investigation, and the development of satisfactory methods of sterilization.
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