Abstract
Summary
1. The pharmacologic responses to the three isomeric thiocyanobenzoic acids have been investigated. 2. The meta and para compounds are powerful depressors. This action is not shared by the ortho compound. 3. p-Thiocyanobenzoic acid inactivates cytochrome oxidase in concentrations similar to cyanide. The meta compound is less active and the ortho isomer exhibits little inhibition. 4. All three isomers are relaxants to smooth muscle.
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