Abstract
Summary
The preparation of a cation exchange indicator compound called quininium resin indicator compound has been described. The rationale and method of its use have been stated.
In vitro tests have demonstrated that the quininium cation present in this compound will be displaced by the hydrogen ions of dilute hydrochloric acid solutions and of the gastric juice.
In vivo experiments have shown that, by administering this cation exchange resin indicator compound orally and noting the time of appearance of the quininium cation in the urine, the presence or absence of free hydrochloric acid in the gastric juice can be determined without subjecting the individual to intubation.
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