Abstract
Summary
1. When performed with inadequate equipment, cross transfusion may be a dangerous procedure. However, it has been shown in experiments on dogs, that with proper apparatus and technic, cross transfusion is safe for both donor and patient.
2. For dogs weighing 10.5 kg or more, the intravenous MLD 100 of mercuric chloride is 2.5 mg/kg.
3. Cross transfusion is an effective means for lowering the non-protein nitrogenous products in the blood of uremic animals.
4. If cross transfusion is started within 90 minutes after intravenous administration of the MLD 100 of mercuric chloride, the test animals remain clinically well and their blood creatinine remains normal or nearly normal.
5. If cross transfusion is started within 180 minutes after intravenous injection of the MLD 100 of mercuric chloride, the test animals become clinically ill and the blood creatinine rises, but the animals eventually recover.
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