Abstract
Summary
Coincident with the development of viral growth and earliest pathology in the brain stem of Lansing poliomyelitis virus inoculated monkeys, there appears to be a marked increase in the metabolic activity of these tissues as regards the phosphate ion. This increase in metabolic activity of the affected brain stem tissues and spinal cord continues to increase during and throughout the period when clinical evidence of weakness, paralysis, and neurologic signs of clinical poliomyelitis exist.
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