Abstract
Conclusions
1. Exteriorization of the antrum of the stomach produces a marked decrease in the secretion of Pavlov pouch dogs comparable to that secured by excision of the antrum. When this exteriorized antrum is subsequently transplanted into the duodenum or into the colon, a marked stimulation of gastric secretion is produced.
2. Transplantation of the antrum of dogs with totally isolated stomach pouches into the duodenum or into the colon produces a marked increase in gastric secretion. These findings support the view that the antrum mucosa is a specific internal secreting organ distinct in function from the mucous membrane of the stomach or duodenum.
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