Abstract
Summary
1. Elinin, a lipoprotein fraction of the red cell exhibiting Rh activity has been isolated in relatively pure form largely by physical methods.
2. Injection of elinin from Rh positive cells into animals has so far failed to yield a measurable titer of anti-Rh antibodies.
3. Injection of elinin into human subjects who have been sensitized to the Rh factor by pregnancy or transfusion failed to increase the titer of Rh antibodies in the serum. Two of the subjects injected showed subsequent response to injection of whole Rh positive cells.
4. Injection of 1 to 1.5 g of active elinin intramuscularly failed to effect a change in titer of circulating antibodies.
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