Abstract
Summary
Albino rats of the Slonaker Strain when kept in a state of hypoglycemia by insulin injections for a period of some hours invariably develop a fatal pulmonary edema. Adrenalectomy and adrenal demedullation reduce the degree of edema but fail to prevent it. Adequate doses of the adrenergic blocking agent, N-(9-fluorenyl)-N-ethyl-β-chlorethylamine-HC1, prevent this hypoglycemia lung edema entirely. It is suggested that this type of pulmonary edema is neurogenic in origin due to the influence of glucose lack on the nerve centers where the vasomotor fibers to the lungs and heart originate.
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