Abstract
Comments and conclusions
The favorable results reported by Shpanir for the benzyl furamide were based on experiments in mice. Though the mouse test is currently in use in several laboratories for screening of compounds for possible antitubercular activity we are not impressed with it as a satisfactory test object(8). It is possible that the present results are at variance with those of Shpanir on account of species differences.
N-Benzyl-2-furamide has no appreciable activity in experimental tuberculosis in guinea pigs. So far the sulfones alone, next to streptomycin, have been demonstrated to have a definitely suppressive effect on this disease.
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