Abstract
Summary
(1) Homologous gamma globulin injected intraperitoneally elevated the level of serum globulin and depressed the albumin without inducing significant albuminuria.
(2) Characteristic glomerular and tubular changes occurred in the animals in which protracted hyperglobulinemia was produced.
(3) Serum protein levels reverted to normal when injections were discontinued.
(4) Glomerulonephritis was not present.
(5) The resemblance of the glomerular lesions to the nodular lesion of intercapillary glomerulosclerosis is noteworthy.
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