Abstract
Summary
1. Methylene blue injected intravenously in doses of 35 mg/K immediately preceding alloxan (30 mg/K i.v.) increased the incidence of diabetes from 52 to 100%.
2. The potentiating effect of methylene blue is attributed, in part at least, to its ability to reoxidize dialuric acid back to alloxan and thereby in effect it is equivalent to increasing the effective dose of alloxan.
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