Abstract
Summary
1. Blood samples taken prior to vaccination and at rather frequent intervals after completion of antirabies vaccination were tested from 18 individuals who received 7 injections of vaccine and from 69 individuals who received 14 injections of vaccine.
2. Both neutralizing and complement-fixing antibodies were induced in the two groups of vaccinated individuals, (but in all instances the neutralizing index reached higher levels and persisted longer than did the complement-fixation titer. The highest antibody levels were attained in those patients who received the greater number of vaccine injections.
3. Four individuals had had antirabies vaccine 6 months to 2 years previously. Three of the 4 still showed an appreciable neutralizing index prior to being revaccinated, and all 4 showed a marked antibody rise or “booster” effect after the second series of vaccine injections.
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