Abstract
Summary
The reaction between desoxyriborauclease and the inhibitor for desoxyribonuclease was found to be of the reversible type, similar to that observed by Kunitz between chymotrypsin α and soybean trypsin inhibitor.
A method for the semi-quantitative evaluation of the inhibitor for desoxyribonuclease has been described. Several normal and pathological tissues were analyzed for both desoxyribonuclease and the inhibitor. Both measurements were influenced by the presence of the second component of the pair.
The inhibitor was found to be readily soluble, while desoxyribonuclease was only slowly liberated into solution from the particulate matter of the cell. Neither of the two components was resistant to the proteolytic enzymes during autolysis, the inhibitor being the least stable of the two.
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