Abstract
Summary and Conclusion
(1) Alloxan diabetes, like pancreatectomy diabetes, interferes with the normal oestrous cycle of rats, and impairs fertility.
(2) Administration of olive oil aids in reversion of the oestrous cycle toward normal, but does not improve fertility.
(3) The course of 11 of the 12 pregnancies reported in this study was uninfluenced by the presence of pre-existing permanent alloxan diabetes.
(4) The course of the diabetes in 5 of the 7 rats observed was not influenced by single or repeated pregnancies.
(5) Two rats died in hypoglycemia, one on the 15th day of pregnancy and one 6 days post partum. The mechanism of this hypoglycemia is unexplained.
(6) Administration of insulin was not required in order to obtain live, full term litters in 10 of the 11 pregnancies observed.
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