Abstract
Summary
Streptomycin PAS may be given intramuscularly without undue irritation. Chemical assay of PAS, and bioassay of streptomycin, each give virtually quantitative recovery of streptomycin PAS in vitro. Following intramuscular administration of streptomycin PAS in human subjects, streptomycin was demonstrated in the plasma and urine within the expected range. PAS also appeared in significant concentrations, but the quantitative relation to streptomycin was altered.
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