Abstract
Summary
Prostigmin was given to young rats in daily amounts of 0.04 to 0.1 mg. The ovaries were slightly increased in weight. The uteri if mature as the result of age or estrogens showed increase in weight following injections of prostigmin and these changes were present after desiccation. Estrous cycles showed no significant change from normal. Cellular elements of inflammatory cells were more abundant in the submucosa after prostigmin. On the whole, pathological changes were not marked; therefore, from the pathological viewpoint effects of prostigmin are minor as far as changes in the ovaries and uterus are concerned.
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