Abstract
Summary
Testosterone propionate definitely increased the cytoplasmic alkaline phosphatase in the follicular cells of the mouse thyroid when dosages of 0.5 mg or more were used. Thiouracil (0.25%) induced marked hyperplasia in 17 days and virtually eliminated the alkaline phosphatase in the follicular epithelium whereas thyroglobulin caused a follicular cell atrophy without loss of the enzyme. Testosterone propionate did not influence the thyroid alkaline phosphatase in the presence of thiouracil or thyroglobulin.
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