Abstract
Summary
After the 300th intracerebral and the 14th intranasal hamster passage, Newcastle disease virus, California strain No. 11,914 can successfully infect hamsters by intradermal injection. The virus in the brain material from each series was passed intradermally in hamsters. Virus was isolated from the brain and cord of hamsters of both series upon inoculation of embryonated chicken eggs. The results of the neutralization tests confirm the virus to be that of Newcastle disease. Hamsters infected intracerebrally, intranasally, and intradermally show similar symptoms, such as involuntary motor reactions, excessive salivation from pharyngeal paralysis, general paralysis, prostration, and death.
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