Abstract
Conclusions and Summary
Intravenous procaine HCl increases cardiac rate and restores a regular sinus rhythm to those hearts showing irregularity during cyclopropane anaesthesia. This may account for the favorable clinical impressions on the use of procaine HCl.
A protecting action against cyclopropane-epinephrine induced ventricular tachycardia and fibrillation with doses of procaine HCl reasonable for prophylactic purposes during anaesthesia could not be demonstrated. In our opinion such protection has not yet been demonstrated by others.
Under the conditions of the experiment the predominating effect of procaine HCl given intravenously was an anti-vagal one.
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