Abstract
Summary
Sulfomucopolysaccharides (sodium heparinate and the sodium salt of agar acid) suppress the growth of cells from methyl cholanthrene tumors in the rat in vitro. To ascertain whether the substances in question had a similar effect on growing tissues in vivo mice were inoculated intraperitoneally with the suspension of cells from Ehrlich's carcinoma, after which they were treated in various ways with sodium heparinate and with sodium salt of agar acid. It was found that the mortality of the control animals was greater than that of the treated animals. The results and various possible explanations are discussed.
Get full access to this article
View all access options for this article.