Effect of Thyroxine on Lymphoid Tissue Mass of Adult Male Mice. ∗

Abstract

Summary

The administration of thyroxine to adult male mice resulted in an increase in the organ weights of the kidneys, spleen, and peripheral lymph nodes. Similar treatment of adrenalectomized animals resulted in an increase in the weights of the spleen and peripheral lymph nodes over and above that which followed adrenalectomy alone. It is concluded that thyroxine produces an increase of lymphoid tissue mass which is independent of the rate of body growth and of the level of adrenal cortical activity.