Abstract
Summary and Conclusion
1) Sodium benzoate administered intravenously and orally to rabbits and one human subject was found to depress the level of glutamine in the blood plasma.
2) The intravenous administration of sodium benzoate produced a rise in the total reducing substances in the blood which was highest with the smallest doses of benzoate.
3) The changes in the glutamine level were not related to either the change of the total amino acid level or the level of total reducing substances in the blood.
4) It is suggested that amidation may be either directly or indirectly depressed by the administration of sodium benzoate.
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