Abstract
Summary
The pharmacological properties of an enzymatically formed product described recently by Nachmansohn, Hestrin and Voripaieff have been tested. This product, obtained in the choline acetylating system derived from brain extracts, is distinctly different from acetylcholine but has an acetylcholine-like action in the bioassay with frog rectus.
In the present paper the acetylcholine-like action of the product has been confirmed and extended. The product decreases the arterial blood pressure of cats and the amplitude of the isolated frog heart in the same way as acetylcholine. Atropine regularly suppresses both actions.
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