Abstract
Summary
Severely diabetic depancreatized male rats reacted as usual to protamine zinc insulin administration by reducing their food intake but gaining weight through a reduction in the glycosuria. Desoxycorticosterone acetate in large doses was without measurable influence on the body weight gain or glycosuria. The glycosuria of the severely diabetic rat without insulin therapy and receiving food ad libitum was unaffected by similar doses of desoxycorticosterone acetate.
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