Abstract
Summary
1. Five patients moderately to severely ill with myasthenia gravis received 400 mg adrenocorticotrophic hormone given in amounts of 20 mg every 6 hours.
2. Changes that may indicate the beginnings of an incomplete remission occurred after completion of the injections. These changes consisted of decrease of the symptoms and outward manifestations of muscle dysfunction, disappearance of the abnormalities noted in the electromyogram, increased work performance on the ergograph, and increase to normal of the ability of serum to support acetylcholine synthesis. The incomplete remission is long lasting.
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