Abstract
Summary
1. Testicular hyaluronidase in bulk assaying 150 TRU per mg is stable at room temperature for more than one year.
2. Hyaluronidase in concentrated aqueous solution is stable for several months at 10°.C Dilute solutions of the enzyme are less stable.
3. Hyaluronidase dried from the frozen state in vials can be stabilized by the addition of polypeptide. Its half-life at 60°C is thereby extended 10 to 20 times.
4. Certain bacteriostatic agents can be used throughout the production of hyaluronidase without decreasing the activity of the enzyme.
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