Abstract
Summary and Conclusions
Golden hamsters (Cricetus auratus) from two different sources were found to present marked differences in their susceptibility to the Lansing strain of poliomyelitis virus. Both strains were found to be markedly inferior to the white mouse and to the cotton rat as experimental animals for poliomyelitis research.
The adjustment of the inoculum at a low pH did not increase the titer of the hamster passage virus consistently. The use of the autolyzed normal mouse brain technic did not increase the infectivity of the virus for the hamster.
The intraperitoneal inoculations of mouse-passage and cotton-rat passage virus resulted in higher titers of neutralizing antibody in the golden hamster than when hamster passage virus was used.
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