Abstract
Conclusions
(1) Doses of urethane simulating those used in the topical treatment of infected wounds in man are not productive of toxic parenchymal changes in the organs of guinea pigs subjected to prolonged daily subjcutaneous injections. The animals remained healthy and gained weight.
(2) A marked mesenchymal cells reaction was consistently seen in the lungs and to a lesser extent in the liver and myocardiuim of urethane treated animals.
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