Abstract
Summary
The theory that the acetyl-choline-cholinesterase system is concerned with membrane permeability is further substantiated by the finding that the L-isomer of isoamidone which has a greater inhibitory action on cholinesterase than has the D-isomer also changes permeability of dog erythrocytes to a different degree than does the D-isomer.
The conditions under which the L has a greater effect than the D-isomer on permeability are a medium containing a high proportion of K ions relative to Na ions.
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