Abstract
Summary
A concentration of 10−5 M: Zn++ failed to affect the serum alkaline phosphatase activity in individuals either with or without cancer. These results are not in agreement with the findings of Roche et al. 1,2 that this concentration of Zn++ activates the serum alkaline phosphatase activity of individuals without cancer and inhibits this activity in patients with cancer. Concentrations of 10−4 and 10−3 M decreased the serum alkaline phosphatase activity, but the extent of these decreases was the same in patients with and without malignancy.
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