Abstract
Conclusions
1. Changes in the gastric mucosa produced by continuous irritation are described.
2. The sequence of events following irritation is compared in colon, small bowel, and stomach.
3. The process of regeneration after superficial destruction of the mucosa is described and is offered as a possible simple explanation for the resistance of the stomach to auto-digestion.
4. The possible implication of this mechanism in the pathogenesis of gastric ulceration is suggested.
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