Abstract
Summary
1. The alveolar O2, CO2 tension and R.Q., minute volumes and respiratory rates have been recorded continuously in animals and man under pentothal sodium anesthesia administered by single and intermittent injection.
2. When the alveolar gas concentrations are plotted with the aid of a CO2-O2 diagram a typical anesthesia pattern can be shown indicating the regions of depression, compensation and recovery.
3. With intermittent injections of pentothal sodium this typical pattern is repeated.
4. The theoretical significance of this respiratory pattern and its utilization for analysis of quantitative changes in respiration in the study of anesthetic agents is discussed.
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