Abstract
Summary
When a subcutaneous inflammation is induced in the mouse through mechanical injury, and when, into such a traumatized site a fragment of experimental sarcoma is deposited, a striking edematous reaction ensues, accompanied by a conspicuous acceleration of tumor growth; these associated phenomena being well defined by the 4th to 6th day after implantation.
This effect is construed as a specific interaction between the neoplastic characteristics of the tumor fragment and the cellular and/or vascular sequences of subcutaneous inflammation. The effect does not occur when nonmalignant tissues are similarly implanted.
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