Abstract
Summary
Methionine labelled with radioactive sulphur (S35) was given intravenously to 4 cats, one normal, 3 treated so as to produce varying degrees of atrophy of the acinar tissue of the pancreas. The animals were sacrificed 8 hours after methionine was given, and various tissues were assayed for radioactive sulphur.
In all animals high activity was found in pancreas, small intestine and liver. In the atrophic portion of the pancreas where a ligature had been placed around the body of that gland, low activity was found as contrasted with high activity found in the normal part of the gland. Where atrophy was incomplete, the activity found was intermediate between that of normal and atrophic tissue.
It is concluded that the high activity of radioactive sulphur found in the pancreas of normal cats after administration of labelled methionine represents principally the metabolic activity of the exocrine portion of the pancreas.
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