Abstract
Summary
Cerebral gray matter of hyperthyroid rats does not show the increase of respiration shown by the intact animal or by diaphragm muscle or kidney tissue. Liver tissue shows a highly variable respiration in hyperthyroidism, sometimes being abnormally low. These low-respiring tissues are, however, greatly stimulated by the addition of succinate. It would seem that in hyperthyroid liver there may be a shortage of coenzyme for the glucose-pyruvate cycle. The cytochrome-oxidase system, as judged by succinate response, remains intact or is enhanced.
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