Abstract
Summary and Conclusions
A method is presented by which the spleen may be readily transplanted subcutaneously in dogs and used for intraportal infusions.
Dogs could tolerate more glutamic acid solution without vomiting when it was given either intrasplenically or directly into the portal vein by using the angiostomy technic, as compared to the peripheral venous administration.
The increased tolerance to glutamic acid solution when given intraportally is attributed to the direct passage of these amino acids to the liver where they may be removed from the circulation.
Get full access to this article
View all access options for this article.