Effect of Diethyldithiocarbamate on the Respiration of Active and Blocked Embryonic Cells. ∗

Abstract

Summary and Conclusion

1. A study has been made on the effects of sodium diethyldithiocarbamate on the oxygen consumption of mitotically active and blocked embryonic cells of the embryo of the grasshopper, Melanoplus differentialls.

2. No significant differences in response of the active and blocked cells to the reagent are noted.

3. In general, diethyldithiocarbamate produces stimulation in low doses and in high doses an initial inhibition followed by a marked stimulation in the oxygen intake of embryonic cells.

4. Partial recovery from high initial doses of the reagent occurs.

5. Copper salts are markedly antagonized when in the presence of the carbamate.