Abstract
Summary
Further evidence has been added to indicate that ethyl alcohol is an alarming stimulus. We have shown that the non-specific stimuli, 4% formaldehyde and 40% glucose, in unadrenalectomized mice temporarily inhibit growth or produce temporary regression of the malignant lymphoid tumor 6C3HED. A similar effect is produced by a 48-hour fast. Fasting begun 30 hours after the initial stimulus gives an additional “lympholytic” effect.
It has been shown that stimuli which are known to produce an alarm reaction with resulting atrophy of the normal thymus and normal spleen produce a similar type of reaction in tissue composed of malignant lymphocytes.
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