Abstract
Summary
About 20% of the young rats weaned from dams fed a synthetic type diet deficient in folic acid developed hydrocephalus. This abnormality could be largely prevented by the addition of pteroylglutamic acid to the maternal diet. Decreasing the vitamin A content of the diet to a low level did not increase the incidence of the hydrocephalus. There was no difference in either the moisture content of the brains or in the cerebrospinal fluid pressure of rats from the stock colony and those from dams receiving a synthetic type ration.
Get full access to this article
View all access options for this article.