Abstract
Summary
1. No inhibition of tumors was noted in Bagg-albino strain mice with spontaneous mammary carcinoma over one cm in size when treated with whole culture lysate of T. cruzi; on the other hand in the same mouse strain with tumors under one cm in size a degree of inhibition was noted which warrants closer study.
2. The inhibition noted could not be attributed to malnutrition effects or concurrent bacterial infections.
3. No inhibition was noted in tumor-bearing “A” strain mice (spontaneous mammary carcinoma; transplanted carcinoma No. 119) when treated with T. cruzi whole culture lysates.
4. Survival time of treated tumor-bearing mice was less than that of control treated animals.
5. A simple method is given for a reproducible preparation of T. cruzi lysates.
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