Occurrence of Rabies Virus in the Blood of Developing Chick Embryo

Abstract

Summary and Comments

The Flury strain of rabies virus was inoculated by the yolk-sac route into 7-day-old chick embryos. By means of intracerebral injections into mice, the virus was recovered from the chick-embryo blood secured from the 3rd to the 15th post inoculation day. The similar results obtained in two series of experiments seem to exclude the possibility of a major experimental error. While these experiments do not prove or disprove the infectiousness of mammalian blood from rabies infected animals, they do indicate a completely different mechanism of dissemination of the virus in embryonated eggs.