Abstract
Summary
The volume of distribution of inulin has been determined by a priming dose and a constant intravenous infusion to insure uniform distribution throughout the extracellular space, followed by collection of the total inulin excreted in the urine after the infusion is discontinued. The inulin space in the dogs ranges from 20.9 to 23.2% of the body weight (average 21.6) and in man from 15 to 16%, as compared with larger spaces obtained with thiocyanate, bromide and sodium.
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