Radiation-Induced Hemorrhagic Disease in Chickens. ∗

Abstract

Summary

In order to study the hemorrhagic disease resulting from radiation, we produced severe radiation injury by repeated subcutaneous injections of P³² into young chicks. Agranulocytosis and thrombocytopenia developed rapidly and during the same period the clotting mechanism of the blood was altered. However, there was no significant increase in coagulation time as found in animals and the hemorrhagic disease which developed was much less severe than that seen in animals. The increased number of mast cells associated with atomic bomb radiation injury in humans was not seen in the chickens.