Abstract
Summary
Ascorbic acid was found in the stomach and small intestine of adult guinea pigs maintained on a diet devoid of the vitamin. The amount present varied with the length of time after intraperitoneal injection of the substance, the maximum occurring at 4 hours. Small amounts only were found in the contents of the cecum and large intestine. The results suggest that the vitamin is excreted into the stomach and small intestine and is destroyed in the cecum.
The maximum content of ascorbic acid was found in the blood and kidneys 1 hour after injection, in the liver 2 hours after injection, and the maximum excretion in the urine occurred between the second and third hours after injection.
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